Original Article Impact of sodium and ultrafiltration profiling on haemodialysis-related hypotension

Background. Symptomatic hypotension is the most frequent complication in patients receiving haemo-dialysis (HD). Previous studies have reported that the use of modulating dialysate sodium concentration or ultrafiltration (UF) rates, or the combination use of sodium profile and UF profile may better preserve blood volume and reduce the incidence of hypotensive episodes. The aim of this study was to evaluate the effects of sodium balance-neutral sodium profile and UF profile and their combination on preservation of blood volume, cardiac function and occurrence of hypotensive episodes. Methods. Using Fresenius MC 4008S, eight stable HD patients underwent four treatments: (1) control, constan