proteomics: efforts towards a comprehensive analysis of membrane proteins in the brain Kathleen J.Grant and Christine C.Wu Proteomic investigation of normal and diseased brain states has the potential to reveal novel molecular therapeutic and diagnostic targets for a multitude of pathological central nervous system conditions. Due to their unique properties, integral membrane proteins are likely to play a central role in the aetiology of these disorders. These properties, however, have prevented comprehensive analysis of this important class of proteins. Recent advances in sample preparation and proteomic quantification platforms, specifically focused on recovery and enrichment of integral membrane proteins, are discussed. Keywords: membran...
The continuing improvement and refinement of proteomic and bioinformatic tools has made it possible ...
Brain disorders affect the normal functionality of the brain causing inability in controlling certai...
Proteomics offers the opportunity elucidate the complex protein interactions of cellular systems by ...
proteomics: efforts towards a comprehensive analysis of membrane proteins in the brain Kathleen J.Gr...
Neuroproteomics is a powerful platform for targeted and hypothesis driven research, providing compre...
Neuroproteomics is a powerful platform for targeted and hypothesis driven research, providing compre...
The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry ou...
Brain proteomics has become a method of choice that allows zooming-in where neuropathophysiological ...
Mammalian brain is challenging to study due to its heterogeneity and complexity. However, recent adv...
The enormous complexity of the central nervous system has impeded its systemic exploration for decad...
Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used...
The mammalian nervous system is an immensely heterogeneous organ composed of a diverse collection of...
Acute brain slices are a sample format for electrophysiology, disease modeling, and organotypic cult...
Similarly to the amazon rainforest which is formed by a multitude of different trees, many of them g...
International audienceThe blood-brain barrier (BBB) regulates the passage of endogenous and exogenou...
The continuing improvement and refinement of proteomic and bioinformatic tools has made it possible ...
Brain disorders affect the normal functionality of the brain causing inability in controlling certai...
Proteomics offers the opportunity elucidate the complex protein interactions of cellular systems by ...
proteomics: efforts towards a comprehensive analysis of membrane proteins in the brain Kathleen J.Gr...
Neuroproteomics is a powerful platform for targeted and hypothesis driven research, providing compre...
Neuroproteomics is a powerful platform for targeted and hypothesis driven research, providing compre...
The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry ou...
Brain proteomics has become a method of choice that allows zooming-in where neuropathophysiological ...
Mammalian brain is challenging to study due to its heterogeneity and complexity. However, recent adv...
The enormous complexity of the central nervous system has impeded its systemic exploration for decad...
Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used...
The mammalian nervous system is an immensely heterogeneous organ composed of a diverse collection of...
Acute brain slices are a sample format for electrophysiology, disease modeling, and organotypic cult...
Similarly to the amazon rainforest which is formed by a multitude of different trees, many of them g...
International audienceThe blood-brain barrier (BBB) regulates the passage of endogenous and exogenou...
The continuing improvement and refinement of proteomic and bioinformatic tools has made it possible ...
Brain disorders affect the normal functionality of the brain causing inability in controlling certai...
Proteomics offers the opportunity elucidate the complex protein interactions of cellular systems by ...