Add to ORKGis defective in a functional Ga2 subunit of a G protein and is characterized by a complete blockade of the cyclic AMP-mediated sensory transduction steps, including cyclic AMP relay, chemotaxis and the cyclic GMP response. Folic acid-mediated transmem-brane signal transduction was investigated in this mutant; the results show that: (1) cell surface folic acid receptors are present in fgdA mutants. (2) Folic acid induces intracellular responses, including acti-vation of guanylate cyclase and chemotaxis. (3) The inhibitory effect of GTP on folic acid binding to membranes is present. (4) GTPyS binding and high-affinity GTPase are stimulated by folic acid. These data strongly suggest that folic acid receptors are coupled to guanylate cyclase an...
Abstract. Evidence is presented for Ca 2+ and cyclic GMP being involved in signal transduction betwe...
The chemoattractant cAMP induces directed cell locomotion in Dictyostelium cells. Several second mes...
Chemoattractants transiently activate guanylyl cyclase in Dictyostelium discoideum cells. Mutant ana...
is defective in a functional Ga2 subunit of a G protein and is characterized by a complete blockade ...
Folic acid and cAMP are chemoattractants in Dictyostelium discoideum, which bind to different surfac...
Transmembrane signal transduction was investigated in four Dictyostelium discoideum mutants that bel...
Transmembrane signal transduction was investigated in four Dictyostelium discoideum mutants that bel...
Abstract. Transmembrane signal transduction was in-vestigated in four Dictyostelium discoideum utant...
A Dictyostelium discoideutn mutant defective in folate chemotaxis has been analysed using bio-chemic...
A combined biochemical and genetic approach was used to show that phospholipase C in the cellular sl...
A combined biochemical and genetic approach was used to show that phospholipase C in the cellular sl...
Dictyostelium cells use extracellular cyclic AMP both as a chemoattractant and as a morphogen induci...
A combined biochemical and genetic approach was used to show that phospholipase C in the cellular sl...
Aggregating Dictyostelium cells secrete cAMP during cell aggregation, cAMP induces two fast response...
Chemotactic stimulation of post-vegetative Dictyostelium cells with folic acid or aggregative cells ...
Abstract. Evidence is presented for Ca 2+ and cyclic GMP being involved in signal transduction betwe...
The chemoattractant cAMP induces directed cell locomotion in Dictyostelium cells. Several second mes...
Chemoattractants transiently activate guanylyl cyclase in Dictyostelium discoideum cells. Mutant ana...
is defective in a functional Ga2 subunit of a G protein and is characterized by a complete blockade ...
Folic acid and cAMP are chemoattractants in Dictyostelium discoideum, which bind to different surfac...
Transmembrane signal transduction was investigated in four Dictyostelium discoideum mutants that bel...
Transmembrane signal transduction was investigated in four Dictyostelium discoideum mutants that bel...
Abstract. Transmembrane signal transduction was in-vestigated in four Dictyostelium discoideum utant...
A Dictyostelium discoideutn mutant defective in folate chemotaxis has been analysed using bio-chemic...
A combined biochemical and genetic approach was used to show that phospholipase C in the cellular sl...
A combined biochemical and genetic approach was used to show that phospholipase C in the cellular sl...
Dictyostelium cells use extracellular cyclic AMP both as a chemoattractant and as a morphogen induci...
A combined biochemical and genetic approach was used to show that phospholipase C in the cellular sl...
Aggregating Dictyostelium cells secrete cAMP during cell aggregation, cAMP induces two fast response...
Chemotactic stimulation of post-vegetative Dictyostelium cells with folic acid or aggregative cells ...
Abstract. Evidence is presented for Ca 2+ and cyclic GMP being involved in signal transduction betwe...
The chemoattractant cAMP induces directed cell locomotion in Dictyostelium cells. Several second mes...
Chemoattractants transiently activate guanylyl cyclase in Dictyostelium discoideum cells. Mutant ana...