ORIGINAL ARTICLE Imaging Frontostriatal Function in Ultra-High-Risk, Early, and Chronic Schizophrenia During Executive Processing

toms of schizophrenia (ultra-high-risk group) demon-strate impaired performance on tasks of executive func-tion, attention, and working memory. The neurobiological underpinnings of such executive deficits in ultra-high-risk individuals remains unclear. Objective: We assessed frontal and striatal functions dur-ing a visual oddball continuous performance task, in ultra-high-risk, early, and chronic schizophrenic patients with the use of functional magnetic resonance imaging. Design: Cross-sectional case-control design