Color and Power Doppler Sonography Versus DMSA Scintigraphy in Acute Pyelonephritis and in Prediction of Renal Scarring

Capabilities of color and power Doppler sonography (DS) were prospectively evaluated for diagnosis of acute pyelonephritis and for prediction of scarring by comparison with 99mTc-dimer-captosuccinic acid scintigraphy (DMSA). Methods: Fifty-seven children (mean age, 5 3 y) with acute pyelonephritis were investigated by biologic testing, DS (DS 1), and DMSA (DMSA 1). Patients who were 6 mo old or had high-grade reflux or obstruction were excluded. Forty-five children had a clinical follow-up examination, biologic testing, DS (DS 2), and DMSA (DMSA 2) at a mean of 7 2 mo after acute infection. Sonog-raphy (gray-scale and DS) was performed by 1 experienced radiologist who was unaware of patient data. DMSA studies were interpreted by 2 physicians who were unaware of patient data. Results: Temperature, neutrophil count, and C-reactive protein value were significantly higher in patients with abnorma