Molecular sequence is experimentally derived data and can be expected to contain errors at a finite rate as a result of diverse phenomena such as biological variation, molecular cloning artifacts, imperfect sequence determination, and data handling during contig assembly. The presence of errors will affect the reliability of database searches and sequence alignments, but their impact may be minimized by the use of analytic techniques which anticipate the presence of imperfect data.January 7, 2001 page
Widely used approaches for extracting phylogenetic information from aligned sets of molecular sequen...
DNA is an attractive digital data storing medium due to high information density and longevity. Here...
The new generation of short-read sequencing technologies requires reliable measures of data quality....
Background: A feature common to all DNA sequencing technologies is the presence of base-call errors ...
Owing to its longevity and enormous information density, DNA, the molecule encoding biological infor...
35 pages, 1 article*Estimation and Reliability of Molecular Sequence Alignments* (Thorne, Jeffrey L....
International audienceBackground: Multiple Sequence Alignments (MSAs) are the starting point of mole...
Advances in genomics have made whole genome studies increasingly feasible across the life sciences. ...
Motivation: Bioinformatics tools, such as assemblers and aligners, are expected to produce more accu...
Our ability to acquire and analyze DNA sequence data has increased phenomenally in the past 12 years...
Relating a gene mutation to a phenotype is a common task in different disciplines such as protein bi...
<div><p>Relating a gene mutation to a phenotype is a common task in different disciplines such as pr...
Datasets used in the paper titled "Estimating error rates for single molecule protein sequencing exp...
The recent release of twenty-two new genome sequences has dramatically increased the data available ...
The recent release of twenty-two new genome sequences has dramatically increased the data available ...
Widely used approaches for extracting phylogenetic information from aligned sets of molecular sequen...
DNA is an attractive digital data storing medium due to high information density and longevity. Here...
The new generation of short-read sequencing technologies requires reliable measures of data quality....
Background: A feature common to all DNA sequencing technologies is the presence of base-call errors ...
Owing to its longevity and enormous information density, DNA, the molecule encoding biological infor...
35 pages, 1 article*Estimation and Reliability of Molecular Sequence Alignments* (Thorne, Jeffrey L....
International audienceBackground: Multiple Sequence Alignments (MSAs) are the starting point of mole...
Advances in genomics have made whole genome studies increasingly feasible across the life sciences. ...
Motivation: Bioinformatics tools, such as assemblers and aligners, are expected to produce more accu...
Our ability to acquire and analyze DNA sequence data has increased phenomenally in the past 12 years...
Relating a gene mutation to a phenotype is a common task in different disciplines such as protein bi...
<div><p>Relating a gene mutation to a phenotype is a common task in different disciplines such as pr...
Datasets used in the paper titled "Estimating error rates for single molecule protein sequencing exp...
The recent release of twenty-two new genome sequences has dramatically increased the data available ...
The recent release of twenty-two new genome sequences has dramatically increased the data available ...
Widely used approaches for extracting phylogenetic information from aligned sets of molecular sequen...
DNA is an attractive digital data storing medium due to high information density and longevity. Here...
The new generation of short-read sequencing technologies requires reliable measures of data quality....