FDG-PET Appearance of Pelvic Castleman's Disease

We report a case of Castleman's disease demonstrating 18F-fluorodeoxyglucose (FDG) localization by whole-body PET imaging in a pelvic soft-tissue mass shown on abdominopelvic CT. In this case, there is mild FDG localization within pelvic Castleman's disease with standard uptake values lower than in many cases of low-grade and intermediate-grade lymphomas previously reported. FDG-PET may be of value as an imaging modality for differentiating Castleman's disease from lymphoma. Key Words: Castleman's disease; fluorine-18-FDG; PET J NucÃ-Med 1997; 38:1211-1212 V^astleman's disease is a rare benign lymphoproliferative disorder first described in 1954 in a patient with a large mediastinal mass (1,2). Approximately 70 % of lesions occur within the thorax; however, masses may be seen in any region of the body where lymphoid tissue is normally present (3)