Background. Genotypes of the renin-angiotensin system have been implicated in essential hypertension and in progression of native kidney diseases, but gene effects on progression in chronic renal allograft dys-function are unclear. Methods. To examine gene effects on long-term renal allograft function, we conducted a prospective cohort study of 210 nondiabetic renal allograft recipients younger than 36 years of age who underwent trans-plantation between 1980 and 1993 and were followed up through 1999. All grafts survived more than 1 year and all subjects received cyclosporine-based immuno-suppression. DNA was analyzed by polymerase chain reaction for the angiotensin-converting enzyme inser-tion/deletion and angiotensinogen (AGT) M235T poly
A(-20)C polymorphism of the angiotensinogen gene and progression of IgA nephropathy.BackgroundThe M2...
Angiotensin I-converting enzyme (ACE) is crucial in the renin–angiotensin–aldosterone system. ACE in...
Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease.Backgro...
Background. Chronic allograft dysfunction (CAD), the major cause of the failure of kidney allografts...
grantor: University of Toronto'Purpose'. To examine the role of vascular disease-related g...
Background. The angiotensinogen gene has been linked to the development of essential hypertension, a...
Chronic progressive renal function loss is a main cause of long-term graft loss after initially succ...
BACKGROUND: Despite numerous advances in the areas of organ preservation, histocompatibility, and im...
Chronic progressive renal function loss is a main cause of long-term graft loss after initially succ...
Role of genetic variants of the renin-angiotensin system in chronic renal allograft injury. In the v...
Extracellular matrix accumulation in renal tissue is the hallmark of progressive renal function loss...
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: Ris...
BACKGROUND: Angiotensin converting enzyme (ACE) is involved in various pathophysiological condition...
There is a consensus in the scientific literature that supports the importance of the kallikrein kin...
Background: Post-transplant diabetes mellitus (PTDM) is a common and serious metabolic complication....
A(-20)C polymorphism of the angiotensinogen gene and progression of IgA nephropathy.BackgroundThe M2...
Angiotensin I-converting enzyme (ACE) is crucial in the renin–angiotensin–aldosterone system. ACE in...
Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease.Backgro...
Background. Chronic allograft dysfunction (CAD), the major cause of the failure of kidney allografts...
grantor: University of Toronto'Purpose'. To examine the role of vascular disease-related g...
Background. The angiotensinogen gene has been linked to the development of essential hypertension, a...
Chronic progressive renal function loss is a main cause of long-term graft loss after initially succ...
BACKGROUND: Despite numerous advances in the areas of organ preservation, histocompatibility, and im...
Chronic progressive renal function loss is a main cause of long-term graft loss after initially succ...
Role of genetic variants of the renin-angiotensin system in chronic renal allograft injury. In the v...
Extracellular matrix accumulation in renal tissue is the hallmark of progressive renal function loss...
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: Ris...
BACKGROUND: Angiotensin converting enzyme (ACE) is involved in various pathophysiological condition...
There is a consensus in the scientific literature that supports the importance of the kallikrein kin...
Background: Post-transplant diabetes mellitus (PTDM) is a common and serious metabolic complication....
A(-20)C polymorphism of the angiotensinogen gene and progression of IgA nephropathy.BackgroundThe M2...
Angiotensin I-converting enzyme (ACE) is crucial in the renin–angiotensin–aldosterone system. ACE in...
Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease.Backgro...