Add to ORKGterminants that are prognostic for pa-tients with localized prostate cancer. We examined whether cellular levels of the cyclin-kinase inhibitor p27Kip1 (also known as p27) in prostate tumors could be used to predict progression of this disease. Methods: Levels of p27 in tu-mor cell nuclei were assessed by immu-nohistochemical analysis of tissue sec-tions from the primary tumors of 96 patients with stage C prostate carci-noma who had been treated by radical prostatectomy. Tumors were classified into one of the following three groups on the basis of the percentage of tumo
The pre-operative prediction of prognostic tumour features in the radical prostatectomy specimen usi...
The cell-cycle inhibitor p27 is a potential tumor suppressor, but its gene has never been found inac...
Despite its potential role as a tumor suppressor, p27 gene, a member of the Cip/Kip family of cyclin...
grantor: University of Torontop27 is a cyclin-dependent kinase inhibitor capable of induci...
Methods of grading tumors and prognosticating survival rates of cancer patients by determination of ...
p27Kip1, a cyclin-dependent kinase inhibitor, is considered to be a tumor suppressor gene. Absent or...
p27Kip1 has been hypothesized to play a major role in carcinogenesis. Most of the published data rep...
p27(Kip1) is a member of the Cip1/Kip1 family of cyclin-dependent kinase inhibitors and is a potenti...
BackgroundBoth p21WAF1 and p27KIP1 have been reported as prognostic markers predicting biochemical f...
p27Kip1, a cyclin-cdk inhibitor, is a tumor suppressor. An overwhelming amount of data correlate p27...
p27Kip1 is a nuclear member of the Kip/Cip family of cyclin-dependent kinase inhibitors and is a neg...
The expression of cyclin-dependent kinase inhibitor p27(kip1) in human tumors and normal tissues was...
p27, cyclin D1, and retinoblastoma (Rb) protein have been demonstrated using immunohistochemistry in...
Cell cycle progression is regulated by the combined action of cyclins, cyclin-dependent kinases (CDK...
The p27 cyclin-dependent kinase inhibitor is a negative regulator of cell-cycle progression. In many...
The pre-operative prediction of prognostic tumour features in the radical prostatectomy specimen usi...
The cell-cycle inhibitor p27 is a potential tumor suppressor, but its gene has never been found inac...
Despite its potential role as a tumor suppressor, p27 gene, a member of the Cip/Kip family of cyclin...
grantor: University of Torontop27 is a cyclin-dependent kinase inhibitor capable of induci...
Methods of grading tumors and prognosticating survival rates of cancer patients by determination of ...
p27Kip1, a cyclin-dependent kinase inhibitor, is considered to be a tumor suppressor gene. Absent or...
p27Kip1 has been hypothesized to play a major role in carcinogenesis. Most of the published data rep...
p27(Kip1) is a member of the Cip1/Kip1 family of cyclin-dependent kinase inhibitors and is a potenti...
BackgroundBoth p21WAF1 and p27KIP1 have been reported as prognostic markers predicting biochemical f...
p27Kip1, a cyclin-cdk inhibitor, is a tumor suppressor. An overwhelming amount of data correlate p27...
p27Kip1 is a nuclear member of the Kip/Cip family of cyclin-dependent kinase inhibitors and is a neg...
The expression of cyclin-dependent kinase inhibitor p27(kip1) in human tumors and normal tissues was...
p27, cyclin D1, and retinoblastoma (Rb) protein have been demonstrated using immunohistochemistry in...
Cell cycle progression is regulated by the combined action of cyclins, cyclin-dependent kinases (CDK...
The p27 cyclin-dependent kinase inhibitor is a negative regulator of cell-cycle progression. In many...
The pre-operative prediction of prognostic tumour features in the radical prostatectomy specimen usi...
The cell-cycle inhibitor p27 is a potential tumor suppressor, but its gene has never been found inac...
Despite its potential role as a tumor suppressor, p27 gene, a member of the Cip/Kip family of cyclin...