Abstract: Identification of hybrid systems is complex because it is not a priori known which data is generated by which discrete mode of the system. A novel procedure is presented for the simultaneous determination of the model parameters and classification of the data. Initial parameter estimates are obtained based on a priori knowledge of the modes of the system. Next, the data points are subsequently classified and with each new classified data point the parameter estimates are refined. The proposed procedure is applied in the estimation of parameters in a hybrid description of calcium cycling in the intact heart. Copyright © 2005 IFA
Computational models of cardiovascular physiology can inform clinical decision-making, providing a p...
Lumped parameter approaches for modelling the cardiovascular system typically have many parameters o...
There are many examples of closed loop lumped parameter cardiovascular system (CVS) models in the li...
Abstract. A central problem in systems biology is to identify param-eter values such that a biologic...
6-pages (invited)Lumped parameter approaches for modeling the cardiovascular system typically have m...
Medical technology has seen impressive success in the past decades, generating novel clinical data a...
The development of mathematical models of physiological systems from measured response data has attr...
Lumped parameter approaches for modelling the cardiovascular system typically havemany parameters o...
Parameter estimation techniques are of ever-increasing interest in the fields of medicine and biolog...
A lumped model of the arterial system has been used in constructing a hybrid mock loop due to its re...
The action potential of a cardiac cell is made up of a complex balance of ionic currents which flow ...
Abstract: We present a novel identification framework that enables the use of first-order methods wh...
peer reviewedLumped parameter approaches for modeling the cardiovascular system typically have many ...
Computational cardiac models provide important insights into the underlying mechanisms of heart func...
To be clinically relevant, mathematical models have to be patient-specific, meaning that their para...
Computational models of cardiovascular physiology can inform clinical decision-making, providing a p...
Lumped parameter approaches for modelling the cardiovascular system typically have many parameters o...
There are many examples of closed loop lumped parameter cardiovascular system (CVS) models in the li...
Abstract. A central problem in systems biology is to identify param-eter values such that a biologic...
6-pages (invited)Lumped parameter approaches for modeling the cardiovascular system typically have m...
Medical technology has seen impressive success in the past decades, generating novel clinical data a...
The development of mathematical models of physiological systems from measured response data has attr...
Lumped parameter approaches for modelling the cardiovascular system typically havemany parameters o...
Parameter estimation techniques are of ever-increasing interest in the fields of medicine and biolog...
A lumped model of the arterial system has been used in constructing a hybrid mock loop due to its re...
The action potential of a cardiac cell is made up of a complex balance of ionic currents which flow ...
Abstract: We present a novel identification framework that enables the use of first-order methods wh...
peer reviewedLumped parameter approaches for modeling the cardiovascular system typically have many ...
Computational cardiac models provide important insights into the underlying mechanisms of heart func...
To be clinically relevant, mathematical models have to be patient-specific, meaning that their para...
Computational models of cardiovascular physiology can inform clinical decision-making, providing a p...
Lumped parameter approaches for modelling the cardiovascular system typically have many parameters o...
There are many examples of closed loop lumped parameter cardiovascular system (CVS) models in the li...