Determinant of intrabolus pressure during esophageal peristaltic bolus transport. Am J Physiol Gastrointest Liver Physiol 264: G407–G413

dorfer. Determinants of intrabolus pressure during esophageal peristaltic bolus transport. Am. J. Physiol. 264 (Gastrointest. Liver physiol. 27): G407-G413, 1993.-Previous manometric studies of esophageal fluid bolus transport in humans have gen-erally ignored the hydrodynamic distinction between intrabolus pressure and pressure within the lumen-occluded, contracting esophageal segment. In this study we obtained concurrent esophageal videofluoroscopic and intraluminal manometric re-cordings in supine normal volunteers using different bolus vol-umes and viscosities and abdominal compression. Intrabolus pressure increased with bolus volume, viscosity, and abdominal compression. Esophageal diameter increased with larger bolus volumes, and this increase was correlated with increases in in-trabolus pressure. Intrabolus pressure was highest in the bolus tail. Peak intraluminal pressures>20 mmHg above basal intra