Liver metastases concern half of patients with colorectal cancer, and are frequently unresectable, jeopardizing patient outcome. Owing to increased efficacy, chemotherapy can render initially inoperable patients amenable to potentially curative resection. The 34 % 5-year and 20 % 10-year survival of patients resected following neoadjuvant chronomodulated chemotherapy with 5-fluorouracil, folinic acid and oxaliplatin is similar to that of patients whose disease was operable at diagnosis. Recently, a group of 16 patients were treated with irinotecan and became resectable after treatment. Their survival (56 % at 3 years) matches that of patients treated with other forms of chemotherapy. The poor prognosis of patients with non-resectable hepati...
Patients with hepatic metastases from colorectal cancer have a poor prognosis, with a median surviva...
The best management choice in colorectal cancer patients with unresectable liver-only metastases sho...
Liver resection offers the only chance of cure for patients with advanced colorectal cancer (CRC). T...
Liver metastases from colorectal cancer (CRC) have a poor prognosis. Despite recent advances in the ...
Surgical resection of liver-only metastases from colorectal cancer has undergone extensive evaluatio...
Liver metastases from colorectal cancer (CRC) have a poor prognosis. Despite recent advances in the ...
Liver is the main target for colorectal cancer (CRC) metastases. About 50% of all patients affected ...
Background/Aims: Hepatic resection in metastatic disease from colorectal cancer offers the best chan...
The prognosis of unresectable metastatic colorectal cancer might be improved if a radical surgical r...
The response rate of patients with unresectable liver-limited metastases of colorectal cancer can be...
Colorectal cancer is a very common malignancy and frequently manifests with liver metastases, often ...
Hepatic metastases represent one of major clinical problems in patients affected by solid tumours be...
This study was performed prospectively to assess the effect of systemic chemotherapy (FOLFIRI protoc...
Liver metastases are found in 40 % to 70 % of patients with a colorectal cancer. In nearly one third...
We have previously reported that neoadjuvant therapy with modified FOLFIRI enabled nearly a third of...
Patients with hepatic metastases from colorectal cancer have a poor prognosis, with a median surviva...
The best management choice in colorectal cancer patients with unresectable liver-only metastases sho...
Liver resection offers the only chance of cure for patients with advanced colorectal cancer (CRC). T...
Liver metastases from colorectal cancer (CRC) have a poor prognosis. Despite recent advances in the ...
Surgical resection of liver-only metastases from colorectal cancer has undergone extensive evaluatio...
Liver metastases from colorectal cancer (CRC) have a poor prognosis. Despite recent advances in the ...
Liver is the main target for colorectal cancer (CRC) metastases. About 50% of all patients affected ...
Background/Aims: Hepatic resection in metastatic disease from colorectal cancer offers the best chan...
The prognosis of unresectable metastatic colorectal cancer might be improved if a radical surgical r...
The response rate of patients with unresectable liver-limited metastases of colorectal cancer can be...
Colorectal cancer is a very common malignancy and frequently manifests with liver metastases, often ...
Hepatic metastases represent one of major clinical problems in patients affected by solid tumours be...
This study was performed prospectively to assess the effect of systemic chemotherapy (FOLFIRI protoc...
Liver metastases are found in 40 % to 70 % of patients with a colorectal cancer. In nearly one third...
We have previously reported that neoadjuvant therapy with modified FOLFIRI enabled nearly a third of...
Patients with hepatic metastases from colorectal cancer have a poor prognosis, with a median surviva...
The best management choice in colorectal cancer patients with unresectable liver-only metastases sho...
Liver resection offers the only chance of cure for patients with advanced colorectal cancer (CRC). T...