ABSTRACT Patches (lateral heterogeneities) of cell surface membrane proteins and lipids have been imaged by a number of different microscopy techniques. This patchiness has been taken as evidence for the organization of membranes into domains whose composition differs from the average for the entire membrane. However, the mechanism and specificity of patch formation are not understood. Here we show how vesicle traffic to and from a cell surface membrane can create patches of molecules of the size observed experimentally. Our computer model takes into account lateral diffusion, barriers to lateral diffusion, and vesicle traffic to and from the plasma membrane. Neither barriers nor vesicle traffic alone create and maintain patches. Only the c...
AbstractIt is shown that investigating the lateral motion of lipids in biological membranes can prov...
We describe how membrane proteins diffuse laterally in the membrane plane together with the lipids s...
The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and li...
AbstractPatches (lateral heterogeneities) of cell surface membrane proteins and lipids have been ima...
AbstractPatches (lateral heterogeneities) of cell surface membrane proteins and lipids have been ima...
AbstractMembrane proteins and lipids often appear to be distributed in patches on the cell surface. ...
AbstractWe test here a previously proposed hypothesis about lateral heterogeneity of cell membranes,...
The exploration of hindered diffusion is crucial to understanding membrane organization and dynamics...
Many crucial cellular processes take place at the plasma membrane. The latter is a complex, two-dime...
Integral membrane proteins are tiny factories with big responsibilities in signaling and transport. ...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
AbstractIt is shown that investigating the lateral motion of lipids in biological membranes can prov...
We describe how membrane proteins diffuse laterally in the membrane plane together with the lipids s...
The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and li...
AbstractPatches (lateral heterogeneities) of cell surface membrane proteins and lipids have been ima...
AbstractPatches (lateral heterogeneities) of cell surface membrane proteins and lipids have been ima...
AbstractMembrane proteins and lipids often appear to be distributed in patches on the cell surface. ...
AbstractWe test here a previously proposed hypothesis about lateral heterogeneity of cell membranes,...
The exploration of hindered diffusion is crucial to understanding membrane organization and dynamics...
Many crucial cellular processes take place at the plasma membrane. The latter is a complex, two-dime...
Integral membrane proteins are tiny factories with big responsibilities in signaling and transport. ...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
There is no comprehensive model for the dynamics of cellular membranes. Even mechanisms of basic dyn...
AbstractIt is shown that investigating the lateral motion of lipids in biological membranes can prov...
We describe how membrane proteins diffuse laterally in the membrane plane together with the lipids s...
The cytoskeleton underlying cell membranes may influence the dynamic organization of proteins and li...