recent study from the German Multi-center acute lymphoblastic leukemia (GMALL) Group reported state-of-the-art treatment results for adult B-ALL,1 a disease subset accounting for less than 5 % of all adult ALL. With very few exceptions, B-ALL exhibits the so-called L3 (Burkitt’s lymphoma-like) morphology, nonrandom translocations involv-ing chromosomes 14, 18, 2 and 8, c-myc gene deregulation, and a mature B-lineage pheno-type with monotypic surface immunoglobulin. In the GMALL study, the remission rate and leukemia-free survival increased from 44 % and 0%, obtained with ALL-type treatment, to 74% and 71 % using an intensive regimen introduced for childhood B-ALL and Burkitt’s lymphoma
From 1994 to 2000, 154 adults with Philadelphia chromosome-positive (Ph(+)) and/or BCR-ABL(+) acute ...
Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has a dismal prognosis. We...
Mehrdad Hefazi, Mark R Litzow Division of Hematology, Mayo Clinic, Rochester, MN, USA Abstract: Acut...
Traditional treatment regimens for adult acute lymphoblastic leukemia, including allogeneic hematopo...
International audiencePURPOSE:This study evaluated the efficacy of pediatric-like acute lymphoblasti...
Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL) is the most common subtype o...
Philadelphia chromosome positive (Ph+) acute lympho-blastic leukemia (ALL) includes at least one-qua...
Acute lymphoblastic leukemia (ALL) is the most frequent neoplastic disease in children, being a rare...
BCR-ABL, t(4;11)/MLL-AF4, t(1;19)/E2APBX1, 901p15-p16 deletions, 6q deletions, miscellaneous structu...
Patients with acute lymphoblastic leukemia (ALL) are characterized by an unfavorable outcome in the ...
Patients with acute lymphoblastic leukemia (ALL) are characterized by an unfavorable outcome in the ...
With intensified pediatric-like therapy and genetic disease dissection, the field of adult acute lym...
Adult acute lymphoblastic leukemia (ALL) is a sig-nificantly different disease when compared to chil...
From 1994 to 2000, 154 adults with Philadelphia chromosome-positive (Ph+) and/or BCR-ABL(+) acute ly...
To shed light into the molecular bases of B-lineage acute lymphoblastic leukemia lacking known fusio...
From 1994 to 2000, 154 adults with Philadelphia chromosome-positive (Ph(+)) and/or BCR-ABL(+) acute ...
Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has a dismal prognosis. We...
Mehrdad Hefazi, Mark R Litzow Division of Hematology, Mayo Clinic, Rochester, MN, USA Abstract: Acut...
Traditional treatment regimens for adult acute lymphoblastic leukemia, including allogeneic hematopo...
International audiencePURPOSE:This study evaluated the efficacy of pediatric-like acute lymphoblasti...
Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL) is the most common subtype o...
Philadelphia chromosome positive (Ph+) acute lympho-blastic leukemia (ALL) includes at least one-qua...
Acute lymphoblastic leukemia (ALL) is the most frequent neoplastic disease in children, being a rare...
BCR-ABL, t(4;11)/MLL-AF4, t(1;19)/E2APBX1, 901p15-p16 deletions, 6q deletions, miscellaneous structu...
Patients with acute lymphoblastic leukemia (ALL) are characterized by an unfavorable outcome in the ...
Patients with acute lymphoblastic leukemia (ALL) are characterized by an unfavorable outcome in the ...
With intensified pediatric-like therapy and genetic disease dissection, the field of adult acute lym...
Adult acute lymphoblastic leukemia (ALL) is a sig-nificantly different disease when compared to chil...
From 1994 to 2000, 154 adults with Philadelphia chromosome-positive (Ph+) and/or BCR-ABL(+) acute ly...
To shed light into the molecular bases of B-lineage acute lymphoblastic leukemia lacking known fusio...
From 1994 to 2000, 154 adults with Philadelphia chromosome-positive (Ph(+)) and/or BCR-ABL(+) acute ...
Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has a dismal prognosis. We...
Mehrdad Hefazi, Mark R Litzow Division of Hematology, Mayo Clinic, Rochester, MN, USA Abstract: Acut...