ABSTRACT: The purpose of the present investigation was to achieve successful delivery specifically to the colon using guar gum and HPMC K4M as a compression coat over a core tablet of ibuprofen. In this study, Guar gum along with Hydroxy Propyl Methyl Cellulose (HPMC) was used as a compression-coating polymer. The drug delivery system was based on the gastrointestinal transit time concept, assuming colon arrival time to be 6 h. rapidly disintegrating core tablets containing 100-mg ibuprofen were compression coated with guar gum and HPMC. A 32 full factorial design was applied for optimization of the formulation. Both variables, coat weight of the tablet (X1) and the proportion of guar gum in polymer blend (X2) and, had an influence on the p...
Mastic gum has been reported to possess considerable anti-tumor activity against human colorectal ca...
The aim of present investigation deals with the development of time-dependent and p...
The colon is being extensively investigated as a drug delivery site. Colonic drug delivery is a rela...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
The major intention to formulate and develop colon targeted tablets is to improve the therapeutic ef...
The present investigation deals with to formulation and evaluation of colon specific drug delivery s...
The present investigation deals with to formulation and evaluation of colon specific drug delivery s...
The present investigation deals with to formulation and evaluation of colon specific drug delivery s...
Purpose: The aim of the present study was minimizing the drug release in upper gastro intestinal tra...
The aspiration of present work is to design a colon specific drug delivery of mefenamic acid (MA) by...
Mesalamine is a gold standard anti-inflammatory drug used to treat inflammatory bowel illnesses. It'...
For the purpose of colonic drug-targeting, poly(ether-ester) azopolymers were synthesized and used t...
In the present work, lornoxicam (LOR) loaded guar gum microspheres were prepared and characterized f...
Objective: The objective of this research is to design and evaluate a colon specific drug delivery o...
Mastic gum has been reported to possess considerable anti-tumor activity against human colorectal ca...
Mastic gum has been reported to possess considerable anti-tumor activity against human colorectal ca...
The aim of present investigation deals with the development of time-dependent and p...
The colon is being extensively investigated as a drug delivery site. Colonic drug delivery is a rela...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
The major intention to formulate and develop colon targeted tablets is to improve the therapeutic ef...
The present investigation deals with to formulation and evaluation of colon specific drug delivery s...
The present investigation deals with to formulation and evaluation of colon specific drug delivery s...
The present investigation deals with to formulation and evaluation of colon specific drug delivery s...
Purpose: The aim of the present study was minimizing the drug release in upper gastro intestinal tra...
The aspiration of present work is to design a colon specific drug delivery of mefenamic acid (MA) by...
Mesalamine is a gold standard anti-inflammatory drug used to treat inflammatory bowel illnesses. It'...
For the purpose of colonic drug-targeting, poly(ether-ester) azopolymers were synthesized and used t...
In the present work, lornoxicam (LOR) loaded guar gum microspheres were prepared and characterized f...
Objective: The objective of this research is to design and evaluate a colon specific drug delivery o...
Mastic gum has been reported to possess considerable anti-tumor activity against human colorectal ca...
Mastic gum has been reported to possess considerable anti-tumor activity against human colorectal ca...
The aim of present investigation deals with the development of time-dependent and p...
The colon is being extensively investigated as a drug delivery site. Colonic drug delivery is a rela...