Wallerian Degeneration of the Pontocerebellar Fibers

Summary: Two cases of pontine infarct with Wallerian degeneration (WD) of the pontocerebellar fibers are de-scribed. WD of pontocerebellar fibers, seen bilaterally along the transverse pontine fibers, is more visible in the middle cerebellar peduncles and extends into the white matter of the cerebellar hemispheres. Understanding the anatomy of the white matter and the temporal evolution of this degeneration is essential in identifying WD. Wallerian degeneration (WD) is the process of progressive demyelination and disintegration of the distal axonal segment following the transection of the axon or damage to the neuron. Although this term originally referred to lesions of peripheral nerves, today it can also refer to the CNS when the degener-ation affects a fiber bundle or tract through the sam