Crystal Structure of an RNA Purine-Rich Tetraplex Containing Adenine Tetrads: Implications for Specific Binding in RNA Tetraplexes

mRNA stability (Hew et al., 2000). The fragile X mental retardation protein binds specifically to a purine-rich fragment containing both guanine and adenine in its mRNA (Schaeffer et al., 2001). Mutations in HIV type 1 RNA showed that GA-rich sequences are required fo