Evidence-Based Psychotherapies New Developments in Cognitive- Behavioural Therapy for Depression

system of therapy, mindfulness training Two aspects of the psychotherapy of depression appearmost promising in terms of specific contributions of cognitive-behavioural interventions: first, the use of the therapy in combination with medication, particularly in patients with chronic or resistant conditions; and second, its role in the prevention of relapse or recurrence. Intuitively, it makes sense that the combination of psychotherapy and pharmacotherapy would be superior to either treatment alone. However, only a few studies of good methodological quality have demonstrated this. One such study, published in the New England Journal of Medicine, was by Keller and collaborators from 12 major university health centres (1). This huge randomized con-trolled trial involved over 650 patients with chronic depression and had three treatment arms: medicatio