Add to ORKGprotein, hK7) is a member of the kallikrein family of secreted serine proteases. Reports indicate that in ovar-ian cancer, KLK7 is significantly up-regulated at the mRNA level. The aim of this study was to determine whether hK7, measured quantitatively by ELISA in ovarian cancer cytosols, is a prognostic biomarker for ovarian cancer. Methods: We used a newly developed ELISA with 2 monoclonal antibodies to quantify hK7 production in 260 ovarian tumor cytosols and correlated these data with various clinicopathologic variables and patient outcomes [progression-free survival (PFS) and overall survival (OS)] over a median follow-up period of 52 months. Results: Median (range) hK7 concentration in ovaria
TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases. ...
KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognos...
Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly ...
protein, hK7) is a member of the kallikrein family of secreted serine proteases. Reports indicate th...
Expression of the kallikrein-related peptidase 7 (KLK7) is dysregulated in ovarian cancer. We assess...
Human kallikrein 10 (hK10) is a secreted serine protease that is highly expressed in ovarian tissue....
Abstract Background High-grade serous ovarian cancer ...
Ovarian cancer is one of the common malignant tumors in female reproductive organs. Kallikrein-relat...
Purpose : The discovery of new ovarian cancer biomarkers that are suitable for early disease diagnos...
Purpose : The discovery of new ovarian cancer biomarkers that are suitable for early disease diagnos...
Members of the human kallikrein-related peptidase (KLK) family, including KLK5, have been reported t...
Members of the human kallikrein-related peptidase (KLK) family, including KLK5, have been reported t...
Abstract Background In ovarian cancer, dysregulation ...
BACKGROUND: Early detection of ovarian cancer remains a challenge due to widespread metastases and a...
BACKGROUND: The human kallikrein-related peptidase family consists of 15 genes. Twelve of these gene...
TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases. ...
KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognos...
Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly ...
protein, hK7) is a member of the kallikrein family of secreted serine proteases. Reports indicate th...
Expression of the kallikrein-related peptidase 7 (KLK7) is dysregulated in ovarian cancer. We assess...
Human kallikrein 10 (hK10) is a secreted serine protease that is highly expressed in ovarian tissue....
Abstract Background High-grade serous ovarian cancer ...
Ovarian cancer is one of the common malignant tumors in female reproductive organs. Kallikrein-relat...
Purpose : The discovery of new ovarian cancer biomarkers that are suitable for early disease diagnos...
Purpose : The discovery of new ovarian cancer biomarkers that are suitable for early disease diagnos...
Members of the human kallikrein-related peptidase (KLK) family, including KLK5, have been reported t...
Members of the human kallikrein-related peptidase (KLK) family, including KLK5, have been reported t...
Abstract Background In ovarian cancer, dysregulation ...
BACKGROUND: Early detection of ovarian cancer remains a challenge due to widespread metastases and a...
BACKGROUND: The human kallikrein-related peptidase family consists of 15 genes. Twelve of these gene...
TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases. ...
KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognos...
Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly ...