Keywords:

enc central nervous system (CNS). Hormone action is mediated by T3 receptors (TR) of which there are two subtypes, TRα and TRβ. Specific roles for TR subtypes in CNS development are poorly understood. We maturation of the vertebrate brain. In mammals, T3 has been shown transcriptional repressor, and is highly expressed throughout the Developmental Biology xxx (2008) xxx–xxx YDBIO-04080; No. of pages: 14; 4C: 10, 11 Contents lists available at ScienceDirec