STOICHIOMETRIC VERSUS CATALYTIC USE OF COPPER(I) SALTS IN THE SYNTHETIC USE OF MAIN GROUP ORGANOMETALLICS

Abstract- We review some applications of copper derivatives as synthetic tools: stoichiometric organocopper reagents and organomagnesium derivatives in the presence of catalytic amounts of copper salts are able to give a regioselective addition on to acetylenic substrates and to alkylate alkyl or vinyl halides, bromohydrines, their tosylates and carboxylates, and a large variety of allylic substrates