Alpha-thalassemia is a very common hereditarydisease in Taiwan. The carrier rate is about 3.5 % in the general population.(1) The human α-glo-bin genes consist of two duplicate cis-arranged genes located on the short arms of chromosome 16.(2-4) Deficient α-globin genes affect both fetal hemoglobin (α 2γ 2) and adult hemoglobin (α 2β 2) pro-duction. The homozygous genotype of the α-tha-lassemia-1 has been shown to lead to hydrops fetalis.(5,6) Lin et al. found 20 hydropic fetuses among 10156 births from six maternity hospitals in Taipei city.(7) Eighteen of the cases were studied an
Genetic mutations of the α genes are common worldwide. In Asia and particularly Southeast Asia, they...
One of the more common single-gene disorders worldwide is α-thalassemia, carriers of which are found...
Aims: Alpha (α) thalassaemia may be caused by large deletions of the α globin gene(s), or rarely, no...
Forty-seven Chinese suffering from β thalassemia major and their parents were studied to establish l...
[[abstract]]Hemoglobin (Hb) gene disorders are common inherited diseases in Taiwan. The αα- and ββ-t...
Alpha-thalassaemia is one of the most common human genetic disorders. Couples in which both partners...
Alpha thalassemia disorders are a group of hereditary anemias caused by absent or decreased produc-t...
In Southeast Asia, where thalassemia is prevalent, heterozygous carriers of both β-thalassemia mutat...
Objective: The thalassemias is a group of hereditary disorders with impaired production of functiona...
beta- thalassemia is the most-common genetic disorder of hemoglobin synthesis in Malaysia, and about...
a-Thalassemia is one of the most serious genetically transmitted diseases creating health problems i...
Alpha thalassaemia is the most common autosomal recessive single gene disorder in Southeast Asia, en...
A total of 1,342 blood samples from five aboriginal groupain Taiwan, comprising 522 of the Ami, 24...
identical with Fessas and Papaspyrou hemoglobin-has been found by the author to occur in 3.3 per cen...
This case report highlights the importance for health care providers to be aware of the αlpha‐thalas...
Genetic mutations of the α genes are common worldwide. In Asia and particularly Southeast Asia, they...
One of the more common single-gene disorders worldwide is α-thalassemia, carriers of which are found...
Aims: Alpha (α) thalassaemia may be caused by large deletions of the α globin gene(s), or rarely, no...
Forty-seven Chinese suffering from β thalassemia major and their parents were studied to establish l...
[[abstract]]Hemoglobin (Hb) gene disorders are common inherited diseases in Taiwan. The αα- and ββ-t...
Alpha-thalassaemia is one of the most common human genetic disorders. Couples in which both partners...
Alpha thalassemia disorders are a group of hereditary anemias caused by absent or decreased produc-t...
In Southeast Asia, where thalassemia is prevalent, heterozygous carriers of both β-thalassemia mutat...
Objective: The thalassemias is a group of hereditary disorders with impaired production of functiona...
beta- thalassemia is the most-common genetic disorder of hemoglobin synthesis in Malaysia, and about...
a-Thalassemia is one of the most serious genetically transmitted diseases creating health problems i...
Alpha thalassaemia is the most common autosomal recessive single gene disorder in Southeast Asia, en...
A total of 1,342 blood samples from five aboriginal groupain Taiwan, comprising 522 of the Ami, 24...
identical with Fessas and Papaspyrou hemoglobin-has been found by the author to occur in 3.3 per cen...
This case report highlights the importance for health care providers to be aware of the αlpha‐thalas...
Genetic mutations of the α genes are common worldwide. In Asia and particularly Southeast Asia, they...
One of the more common single-gene disorders worldwide is α-thalassemia, carriers of which are found...
Aims: Alpha (α) thalassaemia may be caused by large deletions of the α globin gene(s), or rarely, no...