Not for general distribution; prepublication print of material to appear in J. Korean Information Science Society. 1 Molecular Computing with Artificial Neurons

Abstract—Today’s computers are built up from a minimal set of standard pattern recognition opera-tions. Logic gates, such as NAND, are common ex-amples. Biomolecular materials offer an alternative approach, both in terms of variety and context sensi-tivity. Enzymes, the basic switching elements in bio-logical cells, are notable for their ability to discrimi-nate specific molecules in a complex background and to do so in a manner that is sensitive to particular mi-lieu features and indifferent to others. The enzyme, in effect, is a powerful context sensitive pattern rec-ognizer. We describe a tabletop pattern processor that in a rough way can be analogized to a neuron whose input-output behavior is controlled by enzy-matic dynamics