Add to ORKGA prospective multi-institutional study has been commenced in Japan to evaluate the feasibility of induction chemotherapy using pemetrexed plus cisplatin, followed by extrapleural pneumonectomy (EPP) and postoperative hemithoracic radiation in patients with resectable malignant pleural mesothelioma. The study was initiated on May 2008 and 40 patients will be recruited over 3 years. Primary endpoints are macroscopic complete resection rate by EPP and treatment-related mortality for trimodality therapy. Secondary endpoints include treatment completion rate, adverse events, response rate by chemotherapy and 2-year overall and relapse-free survival. Key words: extrapleural pneumonectomy – induction chemotherapy – radiotherapy – malignant pleura...
BACKGROUND: Postoperative hemithoracic radiotherapy has been used to treat malignant pleural mesothe...
IntroductionPreviously published results from a randomized phase III study of pemetrexed plus cispla...
BACKGROUND: Postoperative hemithoracic radiotherapy has been used to treat malignant pleural mesothe...
A prospective multi-institutional study has been initiated in Japan to evaluate the feasibility of i...
BACKGROUND: Trimodality therapy seems to be the best treatment for malignant pleural mesothelioma (M...
BACKGROUND: Malignant pleural mesothelioma is an aggressive tumor that has a poor prognosis and is r...
textabstractThe European Organisation for Research and Treatment of Cancer (EORTC; protocol 08031) p...
The European Organisation for Research and Treatment of Cancer (EORTC; protocol 08031) phase II tria...
IntroductionExtrapleural pneumonectomy (EPP) and adjuvant high-dose radiation therapy (RT) are assoc...
BACKGROUND: The aim of this multicenter trial was to prospectively evaluate neo-adjuvant chemotherap...
Introduction:We developed an innovative approach for malignant pleural mesothelioma (MPM) with a sho...
Background: Pemetrexed in combination with cisplatin (Pem/Cis) is used globally for the treatment of...
Malignant pleural mesothelioma (MPM) is an aggressive disease with poor prognosis and the current tr...
OBJECTIVES: While the best approach to malignant pleural mesothelioma has yet to be demonstrated, su...
INTRODUCTION: Previously published results from a randomized phase III study of pemetrexed plus cisp...
BACKGROUND: Postoperative hemithoracic radiotherapy has been used to treat malignant pleural mesothe...
IntroductionPreviously published results from a randomized phase III study of pemetrexed plus cispla...
BACKGROUND: Postoperative hemithoracic radiotherapy has been used to treat malignant pleural mesothe...
A prospective multi-institutional study has been initiated in Japan to evaluate the feasibility of i...
BACKGROUND: Trimodality therapy seems to be the best treatment for malignant pleural mesothelioma (M...
BACKGROUND: Malignant pleural mesothelioma is an aggressive tumor that has a poor prognosis and is r...
textabstractThe European Organisation for Research and Treatment of Cancer (EORTC; protocol 08031) p...
The European Organisation for Research and Treatment of Cancer (EORTC; protocol 08031) phase II tria...
IntroductionExtrapleural pneumonectomy (EPP) and adjuvant high-dose radiation therapy (RT) are assoc...
BACKGROUND: The aim of this multicenter trial was to prospectively evaluate neo-adjuvant chemotherap...
Introduction:We developed an innovative approach for malignant pleural mesothelioma (MPM) with a sho...
Background: Pemetrexed in combination with cisplatin (Pem/Cis) is used globally for the treatment of...
Malignant pleural mesothelioma (MPM) is an aggressive disease with poor prognosis and the current tr...
OBJECTIVES: While the best approach to malignant pleural mesothelioma has yet to be demonstrated, su...
INTRODUCTION: Previously published results from a randomized phase III study of pemetrexed plus cisp...
BACKGROUND: Postoperative hemithoracic radiotherapy has been used to treat malignant pleural mesothe...
IntroductionPreviously published results from a randomized phase III study of pemetrexed plus cispla...
BACKGROUND: Postoperative hemithoracic radiotherapy has been used to treat malignant pleural mesothe...