Insular Infarction Presenting With Transient Global Amnesia

The pathophysiology of transient global amnesia is uncertain. Several studies have suggested that the anatomical substrates of transient global amnesia are the limbic areas, including the hippocampus, caudate nucleus, cingulate area, and thalamus. We examined a patient who presented with transient global amnesia with left insular infarction. We believe that the insular lobe may be an important area of episodic memory formation, and infarction of this brain area may be the mechanism underlying the amnesia experienced in this case