The possibility that cardiac autoimmunity contributes to the pathogenesis of Chagas heart disease is controversial. In this paper, we address the following questions regarding the genesis of autoimmunity in Chagas heart disease: (i) What mechanism(s) are potentially responsible for the generation of self-directed antibodies and lymphocytes? (ii) What is the evidence that any of these mechanisms actually can occur? (iii) What are the implications of the presence of autoimmunity for other mechanisms of cardiac in¯ammation? q 2001 Published by Elsevier Science Ltd. on behalf of Australian Society for Parasitology Inc
Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease. Autoimmune mechanisms m...
Over the past 20 years, the immune effector mechanisms involved in the control of Trypanosoma cruzi,...
Trypanosoma cruzi (T cruzi) is the causative agent of Chagas' disease, an endemic and chronic illnes...
Chagas heart disease is caused by infection with the protozoan parasite Trypanosoma cruzi. The appar...
There are many potential mechanisms underlying the pathogenesis of chagasic heart disease. The frequ...
Chagas' disease is a major health problem in Latin America, where it constitutes one of the leading ...
Up to 18 million of individuals are infected by the protozoan parasite Trypanosoma cruzi in Latin Am...
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal de-struction ar...
Chagas' disease is a major health problem in Latin America, where it constitutes one of the leading ...
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal destruction are...
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal destruction are...
Since more than 30 years, the hypothesis of autoimmunity is considered for chronic Chagas disease, e...
Chagas disease (CD), a neglected tropical disease caused by the protozoan Trypanosoma cruzi, affects...
Chagas disease continues to be a significant public health problem, as ca. 10 million people are sti...
The protozoan Trypanosoma cruzi causes chronic Chagas' disease myocarditis (CCDM) in infected mammal...
Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease. Autoimmune mechanisms m...
Over the past 20 years, the immune effector mechanisms involved in the control of Trypanosoma cruzi,...
Trypanosoma cruzi (T cruzi) is the causative agent of Chagas' disease, an endemic and chronic illnes...
Chagas heart disease is caused by infection with the protozoan parasite Trypanosoma cruzi. The appar...
There are many potential mechanisms underlying the pathogenesis of chagasic heart disease. The frequ...
Chagas' disease is a major health problem in Latin America, where it constitutes one of the leading ...
Up to 18 million of individuals are infected by the protozoan parasite Trypanosoma cruzi in Latin Am...
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal de-struction ar...
Chagas' disease is a major health problem in Latin America, where it constitutes one of the leading ...
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal destruction are...
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal destruction are...
Since more than 30 years, the hypothesis of autoimmunity is considered for chronic Chagas disease, e...
Chagas disease (CD), a neglected tropical disease caused by the protozoan Trypanosoma cruzi, affects...
Chagas disease continues to be a significant public health problem, as ca. 10 million people are sti...
The protozoan Trypanosoma cruzi causes chronic Chagas' disease myocarditis (CCDM) in infected mammal...
Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease. Autoimmune mechanisms m...
Over the past 20 years, the immune effector mechanisms involved in the control of Trypanosoma cruzi,...
Trypanosoma cruzi (T cruzi) is the causative agent of Chagas' disease, an endemic and chronic illnes...
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