1. Coupling of cardiac fibroblasts and myocytes

ibr rdi 1 volume, but they are the minority in terms of cell numbers. nonmyocytes. They are arranged in sheets and strands that run in parallel to the prevailing direction of muscle Journal of ElectrocardiologT Corresponding author. Fax: +44 0 1865 272 554.islands embedded in fibrotic scar tissue. The inherent mechanosensitivity of cardiac fibroblasts could, furthermore, allow them to play a sensory role and to affect cardiac electrophysiology via mechanoelectric feedback. This article reviews the currently available experimental and theoretical evidence on the previous scenarios, and highlights areas for further research