pharmacotherapy for obsessive-compulsive disorder

term outcome. These additional metrics provide a more nuanced view of the strengths and limitations of the amine; SSRI; ERP; CBT; Serotonin reuptake inhibitors; Combined pharmacological and psychotherapeutic interventions Clinical Psychology Review 24 (2004) 1011–1030existing data and their implications for clinical practice. Behavioral and cognitive-behavioral therapy, and a range of pharmacological interventions, lead to substantial improvement for the average patient, with individual psychotherapies and clomipramine and other Serotonin reuptake inhibitors faring best across multiple metrics. However, OCD symptoms persist at moderate levels even following adequate treatment course, and no replicable data are available on maintenance of gains for either form of treatment at 1 year or beyond. Future research should track recruitment and exclusion of study participants, include more comorbid patients, and focus on longer-term follow-up using multiple indices of outcome. More research on combined pharmacological and psychotherapeutic interventions is also indicated