Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines Katherine Macé1,6, Fernando Aguilar1, Jia-Sheng Wang2, position of the codon 250. No significant AFB1-induced p53 mutations could be detected in the T5-2A6 cells. Therefore,Patricia Vautravers1, Maria Gómez-Lechón3, Frank J.Gonzalez4, John Groopman2, Curtis C.Harris5 the differential expression of specific CYP450 genes i
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
The tumor suppressor gene p53 is commonly mutated with high frequencies at certain hot spots in huma...
The tumor suppressor gene p53 is commonly mutated with high frequencies at certain hot spots in huma...
Sequence-dependent formation and lack of repair of polycyclic aromatic hydrocarbon-induced DNA adduc...
Sequence-dependent formation and lack of repair of polycyclic aromatic hydrocarbon-induced DNA adduc...
Mutations in the TP53 tumor suppressor gene are the most common alteration in cancer, and human prim...
International audienceGene expression profiling has recently emerged as a promising approach to iden...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths. Aflatoxins, which ma...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
In liver cancer, aflatoxin B1 is a potent carcinogen and drug resistance is a major obstruction in c...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
The tumor suppressor gene p53 is commonly mutated with high frequencies at certain hot spots in huma...
The tumor suppressor gene p53 is commonly mutated with high frequencies at certain hot spots in huma...
Sequence-dependent formation and lack of repair of polycyclic aromatic hydrocarbon-induced DNA adduc...
Sequence-dependent formation and lack of repair of polycyclic aromatic hydrocarbon-induced DNA adduc...
Mutations in the TP53 tumor suppressor gene are the most common alteration in cancer, and human prim...
International audienceGene expression profiling has recently emerged as a promising approach to iden...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths. Aflatoxins, which ma...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
In liver cancer, aflatoxin B1 is a potent carcinogen and drug resistance is a major obstruction in c...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...
Recent studies of the p53 tumor suppressor locus (designated TP53) in primary hepatocellular carcino...
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inac...