Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line) I was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity. Genes Chrorn Cancer 4:69-74 (1992)
Unbalanced chromosome translocations with breakpoints around 8p12, resulting in loss of distal 8p, a...
The detection of chromosomal translocations by fluorescence in situ hybridization (FISH) is widely p...
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes ...
Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8...
Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8...
In 6 different Burkitt lymphoma cell lines with t(2;8) variant translocations (J1, LY66, LY91, BL21,...
Non-random chromosomal translocations are specifically involved in the pathogenesis of many non-Hodg...
Structural chromosome aberrations are hallmarks of many human genetic diseases. The precise mapping ...
Structural chromosome aberrations are hallmarks of many human genetic diseases. The precise mapping ...
In about 80% of Burkitt's lymphoma cases, the tumour cell harbours a reciprocal chromosomal tran...
Deletion of the long arm of chromosome 6 (6q) is one of the most common chromosomal alterations in h...
terized by chromosomal translocations juxtaposing the c-myc gene on chromosome 8 to one of the immun...
International audienceRecurrent chromosome breakpoints in tumour cells may point to cancer genes, bu...
In a family with a constitutional translocation t(3;6), the oldest member carrying the translocation...
Unbalanced chromosome translocations with breakpoints around 8p12, resulting in loss of distal 8p, a...
The detection of chromosomal translocations by fluorescence in situ hybridization (FISH) is widely p...
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes ...
Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8...
Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8...
In 6 different Burkitt lymphoma cell lines with t(2;8) variant translocations (J1, LY66, LY91, BL21,...
Non-random chromosomal translocations are specifically involved in the pathogenesis of many non-Hodg...
Structural chromosome aberrations are hallmarks of many human genetic diseases. The precise mapping ...
Structural chromosome aberrations are hallmarks of many human genetic diseases. The precise mapping ...
In about 80% of Burkitt's lymphoma cases, the tumour cell harbours a reciprocal chromosomal tran...
Deletion of the long arm of chromosome 6 (6q) is one of the most common chromosomal alterations in h...
terized by chromosomal translocations juxtaposing the c-myc gene on chromosome 8 to one of the immun...
International audienceRecurrent chromosome breakpoints in tumour cells may point to cancer genes, bu...
In a family with a constitutional translocation t(3;6), the oldest member carrying the translocation...
Unbalanced chromosome translocations with breakpoints around 8p12, resulting in loss of distal 8p, a...
The detection of chromosomal translocations by fluorescence in situ hybridization (FISH) is widely p...
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes ...