HIGH AND LOW DOSE CLONIDINE TESTS FOR THE DIAGNOSIS OF GROWTH HORMONE DEFICIENCY

The growth hormone (GH) response to three provocative stimuli was assessed in 15 short nor-mal children (ISS) and 5 children with GH defi-ciency (GHD). The pharmacologic agents used were insulin 0.1 unit/kg TV (IHT), oral clonidine 0.15 mg/m2 (HDCT) and 25 µg irrespective of age and weight (LDCT). Blood glucose and GHwer