Add to ORKGglandin D synthase (L-PGDS) is significantly increased in patients with chronic renal failure, but its diagnostic potential in less advanced stages of renal diseases re-mains to be elucidated. Methods: Six mouse monoclonal antibodies (MAbs) were raised against recombinant human L-PGDS. We constructed a sandwich ELISA with two MAbs that recognized different epitopes with high affinities and assessed its assay performance and clinical utility with urine samples from healthy controls, diabetic patients, and patients with various renal diseases. Results: Western blot analyses with NH2-terminus-truncated L-PGDS mapped the epitopes to Ala23–Val2
Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully el...
Renal targets of autoimmunity in human lupus nephritis (LN) are unknown. We sought to identify autoa...
Abstract Background Despite multiple causes, Chronic Kidney Disease is commonly associated with prot...
AbstractAdvanced Glycation End Products (AGEs) are toxins that are involved in structural and functi...
Tetranor-PGDM is a metabolite of PGD2. Urinary tetranor-PGDM levels were reported to be increased in...
We produced 22 different kinds of monoclonal antibody (Mab) by immunizing mice with human GBM antige...
Nephropathy is among the most frequent complications of diabetes and the leading cause of end-stage ...
Varying degrees of renal injury could lead to different changes in urinary protein composition. We w...
Many diabetic patients suffer from declining renal function without developing albuminuria. To ident...
AbstractPhosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping g...
Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene ther...
AbstractThe blood concentration of intact proinsulin, but not total proinsulin, has been suggested t...
Glutamic acid decarboxylase (GAD) is a major islet cell autoantigen in insulin-dependent diabetes me...
HUMORAL IMMUNITY TO RECOMBINANT HUMAN AUTOANTIGENS IN ORGAN-SPECIFI...
Background/Aim: Phenotype-driven screening of a great pool of randomly mutant mice and subsequent se...
Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully el...
Renal targets of autoimmunity in human lupus nephritis (LN) are unknown. We sought to identify autoa...
Abstract Background Despite multiple causes, Chronic Kidney Disease is commonly associated with prot...
AbstractAdvanced Glycation End Products (AGEs) are toxins that are involved in structural and functi...
Tetranor-PGDM is a metabolite of PGD2. Urinary tetranor-PGDM levels were reported to be increased in...
We produced 22 different kinds of monoclonal antibody (Mab) by immunizing mice with human GBM antige...
Nephropathy is among the most frequent complications of diabetes and the leading cause of end-stage ...
Varying degrees of renal injury could lead to different changes in urinary protein composition. We w...
Many diabetic patients suffer from declining renal function without developing albuminuria. To ident...
AbstractPhosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping g...
Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene ther...
AbstractThe blood concentration of intact proinsulin, but not total proinsulin, has been suggested t...
Glutamic acid decarboxylase (GAD) is a major islet cell autoantigen in insulin-dependent diabetes me...
HUMORAL IMMUNITY TO RECOMBINANT HUMAN AUTOANTIGENS IN ORGAN-SPECIFI...
Background/Aim: Phenotype-driven screening of a great pool of randomly mutant mice and subsequent se...
Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully el...
Renal targets of autoimmunity in human lupus nephritis (LN) are unknown. We sought to identify autoa...
Abstract Background Despite multiple causes, Chronic Kidney Disease is commonly associated with prot...