Defective interfering viral particles are readily produced in cell culture after a high multiplicity of infection with many animal RNA viruses. Due to defects that they carry in their genomes, their life cycle needs to be complemented by the helper functions provided by a parental virus which makes them both dependent on and competitive with the parental virus. In many instances, this may cause the abrogation of a lytic cycle of the parental virus, leading to a persistent infection. In this paper, we describe for the first time the presence of truncated or defective interfering viral RNAs produced in Vero cells persistently infected with the flavivirus Murray Valley encephalitis virus. While these RNAs have not been detected in acutely infe...
Our lab was the first to describe and characterize a defective interfering RNA (DI RNAs or DIs) in a...
Potato mop-top virus (PMTV) produces a defective RNA (D RNA) encompassing the 5=-terminal 479 nucleo...
Paramyxoviruses are negative-sense single-stranded RNA viruses that comprise many important human an...
Natural resistance to flaviviruses in mice is controlled by a single genetic locus, Flv, on chromoso...
Defective interfering particles of human parainfluenza virus 3 (HPIV3) were generated and/or amplifi...
Murray Valley encephalitis (MVE) virus strain OR2 was serially passaged on Vero cells to establish a...
RNA viruses exist as a spectrum of mutants that is generated and maintained during replication withi...
The synthesis of virus RNA and proteins in cells infected with two populations of defective virions ...
The synthesis of virus RNA and proteins in cells infected with two populations of defective virions ...
Persistent infections with Orthomyxoviruses have become of increasing interest because of their impl...
AbstractLittle is known about the molecular determinants causing and sustaining viral persistent inf...
A small defective Sendai virus RNA was selectively amplified from a virus preparation obtained after...
Defective interfering particles (DIPs) of vesicular stomatitis virus generated and/or amplified duri...
Copyright © 2014 Wei-Wei Chiang et al.This is an open access article distributed under theCreativeCo...
Poliovirus mutants selected in persistently infected human neuroblastoma cells have a modified cell ...
Our lab was the first to describe and characterize a defective interfering RNA (DI RNAs or DIs) in a...
Potato mop-top virus (PMTV) produces a defective RNA (D RNA) encompassing the 5=-terminal 479 nucleo...
Paramyxoviruses are negative-sense single-stranded RNA viruses that comprise many important human an...
Natural resistance to flaviviruses in mice is controlled by a single genetic locus, Flv, on chromoso...
Defective interfering particles of human parainfluenza virus 3 (HPIV3) were generated and/or amplifi...
Murray Valley encephalitis (MVE) virus strain OR2 was serially passaged on Vero cells to establish a...
RNA viruses exist as a spectrum of mutants that is generated and maintained during replication withi...
The synthesis of virus RNA and proteins in cells infected with two populations of defective virions ...
The synthesis of virus RNA and proteins in cells infected with two populations of defective virions ...
Persistent infections with Orthomyxoviruses have become of increasing interest because of their impl...
AbstractLittle is known about the molecular determinants causing and sustaining viral persistent inf...
A small defective Sendai virus RNA was selectively amplified from a virus preparation obtained after...
Defective interfering particles (DIPs) of vesicular stomatitis virus generated and/or amplified duri...
Copyright © 2014 Wei-Wei Chiang et al.This is an open access article distributed under theCreativeCo...
Poliovirus mutants selected in persistently infected human neuroblastoma cells have a modified cell ...
Our lab was the first to describe and characterize a defective interfering RNA (DI RNAs or DIs) in a...
Potato mop-top virus (PMTV) produces a defective RNA (D RNA) encompassing the 5=-terminal 479 nucleo...
Paramyxoviruses are negative-sense single-stranded RNA viruses that comprise many important human an...