Studies on the nature of immunity to homologous grafted skin, with special reference to the use of pure epidermal grafts

It is now generally accepted that skin does not long survive orthotopic transplanta-tion between animals of ordinary genetic diversity; skin homografts soon break down and slough off as a consequence of an actively acquired immunity reaction on the part of the host (Medawar, 1944, 1945; Dempster, 1951). So far, all attempt