Background: Human kallikrein 7 (hK7), also known as human stratum corneum chymotryptic enzyme, is a chymotrypsin-like serine protease first identified in human skin extracts and predicted to be a secreted pro-tease. The aim of this study was to develop a sensitive and specific immunoassay for hK7 and to examine the distri-bution of hK7 in tissue extracts and biological fluids. Methods: Recombinant hK7 was produced in human embryonic kidney cells (HEK293T) and purified by a three-step column chromatographic procedure. The pu-rified hK7 was injected into mice for antibody genera-tion. A sandwich-type immunoassay was developed with the anti-hK7 monoclonal antibodies. Results: The assay had imprecision (CV) <10 % through the dynamic range of...
BACKGROUND: Human glandular kallikrein 2 (hK2) is expressed in the prostate and is present in serum ...
secreted serine proteases. Some KLKs are established or candidate cancer biomarkers, but for most th...
BACKGROUND: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostat...
Background: Human kallikrein 7 (hK7), also known as human stratum corneum chymotryptic enzyme, is a ...
Background: Human kallikrein 4 (hK4) is a proteolytic enzyme belonging to the tissue kallikrein fami...
also known as normal epithelial cell-specific 1 gene (NES1)] is a member of the human kallikrein gen...
Background: The aims of this study were to develop immunologic reagents and a sensitive and specific...
Summary: An enzyme immunoassay for the determination of human urinary kallikrein has been developed ...
Abstract Background Kallikrein...
Human tissue kallikreins are a family of 15 trypsin or chymotrypsin-like secreted serine proteases (...
Human tissue kallikreins (hKs) form a family of 15 closely related (chymo)trypsin-like serine protei...
Kallikrein-related peptidases (KLKs) are a group of serine proteases widely expressed in various tis...
Background: Human kallikrein 6 (hK6) is significantly increased in serum in many patients with ovari...
BACKGROUND: Human glandular kallikrein 2 (hK2) is expressed in the prostate and is present in serum ...
Background: Human glandular kallikrein (hK2) is a serine protease that has 79 % amino acid identity ...
BACKGROUND: Human glandular kallikrein 2 (hK2) is expressed in the prostate and is present in serum ...
secreted serine proteases. Some KLKs are established or candidate cancer biomarkers, but for most th...
BACKGROUND: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostat...
Background: Human kallikrein 7 (hK7), also known as human stratum corneum chymotryptic enzyme, is a ...
Background: Human kallikrein 4 (hK4) is a proteolytic enzyme belonging to the tissue kallikrein fami...
also known as normal epithelial cell-specific 1 gene (NES1)] is a member of the human kallikrein gen...
Background: The aims of this study were to develop immunologic reagents and a sensitive and specific...
Summary: An enzyme immunoassay for the determination of human urinary kallikrein has been developed ...
Abstract Background Kallikrein...
Human tissue kallikreins are a family of 15 trypsin or chymotrypsin-like secreted serine proteases (...
Human tissue kallikreins (hKs) form a family of 15 closely related (chymo)trypsin-like serine protei...
Kallikrein-related peptidases (KLKs) are a group of serine proteases widely expressed in various tis...
Background: Human kallikrein 6 (hK6) is significantly increased in serum in many patients with ovari...
BACKGROUND: Human glandular kallikrein 2 (hK2) is expressed in the prostate and is present in serum ...
Background: Human glandular kallikrein (hK2) is a serine protease that has 79 % amino acid identity ...
BACKGROUND: Human glandular kallikrein 2 (hK2) is expressed in the prostate and is present in serum ...
secreted serine proteases. Some KLKs are established or candidate cancer biomarkers, but for most th...
BACKGROUND: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostat...