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The rule of thumb I learned in graduate school was that Axis I disorders such as anxiety and depression would bother the patients themselves but that Axis II disorders, the personality disorders, would mostly bother other people. The two categories were presented as discrete entities with a vague relationship that did not interact so much as coexist. Dealing with insurance companies that do not reimburse for working with Axis II disorders meant that I preferred to not diagnose personality disorders, nor to work with them, if I could avoid it. Of course, when working with individuals with depressive disorders, I find not all of them respond favorably to treatments, pharmacological or psychotherapeutic. Also, some people need repeated treatments even after a seemingly successful course. I have also observed that what makes people depressed varies as much as what assists them in recovery. Unfortunately, I have not had an overarching framework that could capture and explain the various forms of training and multitude of experiences I have had. These have remained as discrete as the Axis I and Axis II diagnoses of my graduate training. Bockian's book, Personality-Guided Therapy for Depression, provides a framework for integrating the treatment of depression with personality disorders. It is part of a series of books based in personality-guided psychology, as defined by Theodore Millon. Bockian's book addresses how each of the 10 personality disorders interacts with and defines treatment for depression. Bockian wrote this book at the request of Millon, who i