PS F

ola ina IL-18 binding protein (IL-18BP) is a circulatin formi ve de terfe orms rge als w ge 4– ssay althy (85%) was in its free form. Total IL-18 and IL-18BPa were both elevated in sepsis patients upon admission (1.50.4 ng/ml and 28.64.5 ng/ml, respectively). At these levels, most of the IL-18 is bound to IL-18BPa, however the remaining free IL-18 is still higher than in health