THREATENED ABORTION: A RISK FACTOR FOR POOR PREGNANCY OUTCOME

Abstract- The scientific literature regarding threatened abortion is relatively limited on the subject of outcomes and viability at term. To investigate prospectively the risk of adverse pregnancy outcome in women presenting with first-trimester threatened miscarriage, a prospective case control study was performed on 600 subjects, 150 women presenting with bleeding in the first trimester and 450 asymptomatic age-matched controls. Main outcome measures included gestational age and weight at delivery as well as incidence of adverse pregnancy outcome such as preterm labor, preterm prelabor rupture of membranes (PPROM), placental abruption, and low birth weight (LBW). The first-trimester miscarriage rate in the threatened miscarriage group was 42.7%. Compared with controls, women presenting with threatened miscarriage were more likely to deliver prematurely, 14.7 % compared with 52.9%, respectively (relative risk 3.6, 95 % confidence interval [CI] 2.4-4.8). They were also mor