POINT-COUNTERPOINT COUNTERPOINT Regulation of Oxygen Consumption at Exercise Onset: Is It Really Controversial?

in a unifying scenario. Under “normal ” conditions, during transitions to moderate-intensity exercise, the limiting factor appears to be an inertia of oxidative metabolism. During transitions to exercise of higher metabolic intensity, O2 delivery could play a relatively minor but significant role as a limiting factor. Keywords: skeletal muscle, oxidative metabolism, metabolic regulation, V̇O2 kinetic