c Instituto Politécnico-Universidade do Estado do Rio de Janeiro, IPRJ-UERJ

The chromatographic processes, which are involved by the adsorption-desorption phenomena, correspond to a very important field for separating substances in the chemical and pharmaceutical industry. Among the models of mass transfer kinetics in chromatography, the LDF (linear driving force) and the Langmuir are the most important, being both related with a kinetic of first order [3]. The application of the inverse methodology is a new promising area for obtaining the models parameters from the experimental data [1,2,4]. In this work different kinetic models were analyzed in terms of adsorption and desorption steps of chromatography, applying a inverse problem routine by the Generalized Extremal Optimization Algorithm (GEO). The kinetic models studied correspond to mass balance expressions, as following for the mass balance of solute A in liquid and adsorbent phase, respectively. 1 0 1 1 2.. [.. ( ).] n mA A A A m A A dC c C c C k C q q k q dt 1 2.. ( ). n m