Potent 3-anilino-4-arylmaleimide glycogen synthase kinase-3 (GSK-3) inhibitors have been prepared using automated array methodology. A number of these are highly selective, having little inhibitory potency against more than 20 other protein kinases. (C) 2001 Elsevier Science Ltd. All rights reserved
For the first time, the in silico design, screening, and in vitro validation of potent GSK-3β type-I...
GSK-3 is a serine/threonine kinase that has numerous substrates. Many of these proteins are involved...
An in silico screening procedure was performed to select new inhibitors of glycogen synthase kinase ...
The glycogen synthase kinase-3 (GSK-3) has been linked to the pathogenesis of colorectal cancer, dia...
AbstractBackground: Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the act...
4 p.-4 fig.-1 tab.Glycogen synthase kinase 3 (GSK-3) has become known for its multifactorial involve...
Compound 5 was selected from our in-house library as a suitable starting point for the rational desi...
Compound 5 was selected from our in-house library as a suitable starting point for the rational desi...
Glycogen synthase kinase 3 beta (GSK-3β) is an evolutionarily conserved serine-threonine kinase dysr...
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition o...
A series of novel 3-benzisoxazolyl-4-indolyl-maleimides were synthesized and evaluated for their GSK...
The challenge for glycogen synthase kinase-3 (GSK-3) inhibitor design lies in achieving high selecti...
Inhibiting glycogen synthase kinase-3 (GSK-3) activity via pharmacological intervention has become a...
Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine protein kinase that was o...
Direct inhibitors of glycogen synthase kinase 3β (GSK3β) have been investigated and reported for the...
For the first time, the in silico design, screening, and in vitro validation of potent GSK-3β type-I...
GSK-3 is a serine/threonine kinase that has numerous substrates. Many of these proteins are involved...
An in silico screening procedure was performed to select new inhibitors of glycogen synthase kinase ...
The glycogen synthase kinase-3 (GSK-3) has been linked to the pathogenesis of colorectal cancer, dia...
AbstractBackground: Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the act...
4 p.-4 fig.-1 tab.Glycogen synthase kinase 3 (GSK-3) has become known for its multifactorial involve...
Compound 5 was selected from our in-house library as a suitable starting point for the rational desi...
Compound 5 was selected from our in-house library as a suitable starting point for the rational desi...
Glycogen synthase kinase 3 beta (GSK-3β) is an evolutionarily conserved serine-threonine kinase dysr...
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition o...
A series of novel 3-benzisoxazolyl-4-indolyl-maleimides were synthesized and evaluated for their GSK...
The challenge for glycogen synthase kinase-3 (GSK-3) inhibitor design lies in achieving high selecti...
Inhibiting glycogen synthase kinase-3 (GSK-3) activity via pharmacological intervention has become a...
Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine protein kinase that was o...
Direct inhibitors of glycogen synthase kinase 3β (GSK3β) have been investigated and reported for the...
For the first time, the in silico design, screening, and in vitro validation of potent GSK-3β type-I...
GSK-3 is a serine/threonine kinase that has numerous substrates. Many of these proteins are involved...
An in silico screening procedure was performed to select new inhibitors of glycogen synthase kinase ...