The aim of our work was the detection of c- and N- myc proteins in the developing kidney of human fetuses espe-cially in the neogenous zone. These proteins being localized in nucleus and encoded by the cellullar oncogene myc function as transcriptional factors. Myc gene represents the key control gene in the course of cellular proliferation and differentiation. It also participates in the regulation of apoptosis and the origin of some cancers. Both proteins have been proved to be inevitable for proper nephrogenesis in mice. Considering the dearth of studies dealing with human embryonic tissues, we attempted to map the localization and spatiotemporal relations of the expression of these proteins during human nephrogenesis. In addition, issui...
The identification of the different cell types involved in human nephrogenesis, when solely based on...
The N-myc proto-oncogene is expressed during embryogenesis, suggesting that it plays a role in norma...
Background: The development of the human kidney is a complex process requiring interactions between ...
The myc family of protooncogenes encode similar but distinct nuclear proteins. Since N-myc, c-myc, a...
AbstractN-myc is a transcription factor expressed in the developing metanephric kidney and other org...
The aim of this research was to investigate the expression of proliferation marker Ki-67 and apoptos...
MUC1 is a transmembrane glycoprotein, apically expressed in most epithelial cells, used in the diffe...
The development of the human kidney is a complex process that requires interactions between epitheli...
As metanephric mesenchyme converts into nephrons, the first step is aggregation into a ‘condensate’....
The aim of this study was to better define, by immunohistochemistry, the molecular markers of renal ...
Kidney morphogenesis is a complex and stepwise process. The formation of mature kidney in mammals is...
The development of the human kidney is a complex process that requires interactions between epitheli...
Kidney malformations, such as dysplastic kidneys, are the commonest cause of chronic renal failure i...
A catalogue of gene expression in the developing kidney.BackgroundAlthough many genes with important...
MUC1 is a transmembrane glycoprotein, api-cally expressed in most epithelial cells, used in the diff...
The identification of the different cell types involved in human nephrogenesis, when solely based on...
The N-myc proto-oncogene is expressed during embryogenesis, suggesting that it plays a role in norma...
Background: The development of the human kidney is a complex process requiring interactions between ...
The myc family of protooncogenes encode similar but distinct nuclear proteins. Since N-myc, c-myc, a...
AbstractN-myc is a transcription factor expressed in the developing metanephric kidney and other org...
The aim of this research was to investigate the expression of proliferation marker Ki-67 and apoptos...
MUC1 is a transmembrane glycoprotein, apically expressed in most epithelial cells, used in the diffe...
The development of the human kidney is a complex process that requires interactions between epitheli...
As metanephric mesenchyme converts into nephrons, the first step is aggregation into a ‘condensate’....
The aim of this study was to better define, by immunohistochemistry, the molecular markers of renal ...
Kidney morphogenesis is a complex and stepwise process. The formation of mature kidney in mammals is...
The development of the human kidney is a complex process that requires interactions between epitheli...
Kidney malformations, such as dysplastic kidneys, are the commonest cause of chronic renal failure i...
A catalogue of gene expression in the developing kidney.BackgroundAlthough many genes with important...
MUC1 is a transmembrane glycoprotein, api-cally expressed in most epithelial cells, used in the diff...
The identification of the different cell types involved in human nephrogenesis, when solely based on...
The N-myc proto-oncogene is expressed during embryogenesis, suggesting that it plays a role in norma...
Background: The development of the human kidney is a complex process requiring interactions between ...