The treatment of necrobiosis lipoidica Published by:

at PENNSYLVANIA STATE UNIV on March 6, 2014dvd.sagepub.comDownloaded from Necrobiosis lipoidica is an inflammatory disorder,associated with diabetes mellitus, for which theunderlying pathological mechanism is unknown and for which there is no rational therapy. However, ben-efit has been reported from such different treatment reg-imens as drugs acting on the haemostatic mechanisms, corticosteroid therapy (topical, intralesional and systemic), enhancers of wound healing, surgery and immunomodu-lating therapies (including photochemotherapy). This is a review of these treatment options. Br J Diabetes Vasc Dis 2005;5:37–41 Key words: necrobiosis lipoidica