Neuron e

AMPAR kinetics also depend on TARP expres-sion level, suggesting a variable TARP/AMPAR stoichiometry. Analysis of quantal synaptic transmission in a TARP g-4 knockout (KO) mouse corroborates our expression data and demonstrates that TARP subtype-specific gat-ing of AMPARs contributes to the kinetics of native AMPARs at central synapses