Add to ORKGGrb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxe
Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the ...
The adaptor protein Grb2 links cell-surface receptors, such as Her2, to the multisite docking protei...
The various treatments for advanced gastric cancer have limitations and induce only marginal surviva...
International audienceHER2 represents an important signaling pathway in breast and other cancers. He...
Purpose: Adaptor proteins such as growth factor receptor-bound protein-2 (Grb2) play important roles...
Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the ...
One major trend in modern cancer ther-apy is to develop drugs that target a spe-cific signaling path...
Item does not contain fulltextBACKGROUND: Recently, attention has been focused on molecular targeted...
The human epidermal growth factor receptor (HER) family members are targeted by a growing numbers of...
Advances in anti-cancer drug development have vastly improved cancer treatment strategies over the p...
ABSTRACT The RAF inhibitor vemurafenib (PLX4032) increases survival in patients with BRAF-mutant met...
† These authors contributed equally to this work. * Authors to whom correspondence should be address...
In this thesis we describe a series of studies assessing the effectiveness of targeted therapeutics ...
HER3 belongs to the human epidermal growth factor receptor (HER) family which also includes HER1/EGF...
Background: AIB1 (SRC-3) is an estrogen receptor (ER) co-activator that, when overexpressed in cultu...
Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the ...
The adaptor protein Grb2 links cell-surface receptors, such as Her2, to the multisite docking protei...
The various treatments for advanced gastric cancer have limitations and induce only marginal surviva...
International audienceHER2 represents an important signaling pathway in breast and other cancers. He...
Purpose: Adaptor proteins such as growth factor receptor-bound protein-2 (Grb2) play important roles...
Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the ...
One major trend in modern cancer ther-apy is to develop drugs that target a spe-cific signaling path...
Item does not contain fulltextBACKGROUND: Recently, attention has been focused on molecular targeted...
The human epidermal growth factor receptor (HER) family members are targeted by a growing numbers of...
Advances in anti-cancer drug development have vastly improved cancer treatment strategies over the p...
ABSTRACT The RAF inhibitor vemurafenib (PLX4032) increases survival in patients with BRAF-mutant met...
† These authors contributed equally to this work. * Authors to whom correspondence should be address...
In this thesis we describe a series of studies assessing the effectiveness of targeted therapeutics ...
HER3 belongs to the human epidermal growth factor receptor (HER) family which also includes HER1/EGF...
Background: AIB1 (SRC-3) is an estrogen receptor (ER) co-activator that, when overexpressed in cultu...
Gab2 is a scaffolding protein, overexpressed in many types of cancers, that plays a key role in the ...
The adaptor protein Grb2 links cell-surface receptors, such as Her2, to the multisite docking protei...
The various treatments for advanced gastric cancer have limitations and induce only marginal surviva...