Original Article Guided optimization of fluid status in haemodialysis patients

Background. Achieving normohydration remains a non-trivial issue in haemodialysis therapy. Guiding the haemodialysis patient on the path between fluid overload and dehydration should be the clinical target, although it can be difficult to achieve this target in practice. Objec-tive and clinically applicable methods for the determina-tion of the normohydration status on an individual basis are needed to help in the identification of an appropriate target weight. Methods. The aim of this prospective trial was to guide the patient population of a complete dialysis centre to-wards normohydration over the course of approximately 1 year. Fluid status was assessed frequently (at least monthly) in haemodialysis patients (n = 52) with the bod