Add to ORKGINTRODUCTION. The B cell antigen receptor (BCR) plays an essential role in B cell development, differentiation and function, by controlling survival and proliferation (1). Many of these BCR-controlled responses depend on activation of the small GTPase Ras. Ras exerts its biological effects by controlling multiple effectors, like Raf, PI3K and guanine nucleotide exchang
BackgroundThe B cell antigen receptor (BCR) is a signaling complex that mediates the differentiation...
The multifunctional transforming growth factor 13 receptor (TOR) ligand pair plays a central role in...
The phenotype of hematopoietic cells transformed by the BCR/ABL oncoprotein of the Philadelphia chro...
The GTPase, Ras, is rapidly activated in antigen receptor stimulated T cells, B cells and mast cells...
RasGRP1 is a guanine nucleotide exchange factor (GEF) that activates Ras GTPases downstream of the ...
SummaryEngagement of the B cell antigen receptor (BCR) triggers the Ras cascade, but the biological ...
Immunological interest in small GTPases has focused for some years almost exclusively on the role of...
The B cell receptor (BCR) is a major regulator of B cell development, activation, and cell death. Th...
SummaryB lymphocytes spread and extend membrane processes when searching for antigens and form immun...
Although GTPases of the Ras family have been implicated in many aspects of the regulation of cells, ...
The proper differentiation and survival of human peripheral immature B cells relies on two critical ...
Multiple receptors on the surface of B cells are involved in the regulation of B cell development, ...
BACKGROUND: The B cell antigen receptor (BCR) and pathogen recognition receptors, such as Toll-like ...
The B cell receptor (BCR) activates the ERK kinases, but what does ERK do? In this issue of Immunity...
SummaryIn developing B cells, expression of surface immunoglobulin is an important signal to termina...
BackgroundThe B cell antigen receptor (BCR) is a signaling complex that mediates the differentiation...
The multifunctional transforming growth factor 13 receptor (TOR) ligand pair plays a central role in...
The phenotype of hematopoietic cells transformed by the BCR/ABL oncoprotein of the Philadelphia chro...
The GTPase, Ras, is rapidly activated in antigen receptor stimulated T cells, B cells and mast cells...
RasGRP1 is a guanine nucleotide exchange factor (GEF) that activates Ras GTPases downstream of the ...
SummaryEngagement of the B cell antigen receptor (BCR) triggers the Ras cascade, but the biological ...
Immunological interest in small GTPases has focused for some years almost exclusively on the role of...
The B cell receptor (BCR) is a major regulator of B cell development, activation, and cell death. Th...
SummaryB lymphocytes spread and extend membrane processes when searching for antigens and form immun...
Although GTPases of the Ras family have been implicated in many aspects of the regulation of cells, ...
The proper differentiation and survival of human peripheral immature B cells relies on two critical ...
Multiple receptors on the surface of B cells are involved in the regulation of B cell development, ...
BACKGROUND: The B cell antigen receptor (BCR) and pathogen recognition receptors, such as Toll-like ...
The B cell receptor (BCR) activates the ERK kinases, but what does ERK do? In this issue of Immunity...
SummaryIn developing B cells, expression of surface immunoglobulin is an important signal to termina...
BackgroundThe B cell antigen receptor (BCR) is a signaling complex that mediates the differentiation...
The multifunctional transforming growth factor 13 receptor (TOR) ligand pair plays a central role in...
The phenotype of hematopoietic cells transformed by the BCR/ABL oncoprotein of the Philadelphia chro...