Add to ORKGAbstract: CSF-1 is the major regulator of tissue macrophage development and function. A GM-CSF-dependent, CSF-1 receptor (CSF-1R)-defi-cient F4/80hiMac-1Gr1–CD11c bone marrow macrophage (BMM) line (MacCsf1r/) was devel-oped to study the roles of the eight intracellular CSF-1R tyrosines phosphorylated upon receptor activation. Retroviral expression of the wild-type CSF-1R rescued the CSF-1-induced survival, pro-liferation, differentiation, and morphological char-acteristics of primary BMM. Mutation of all eight tyrosines failed to rescue, whereas the individual
The proliferation, differentiation and survival of mononuclear phagocytes depend on signals from the...
Homozygous mutation of the Csf1r locus (Csf1rko) in mice, rats and humans leads to multiple postnata...
There is recent interest in the role of monocyte/macrophage subpopulations in pathology. How the hem...
Abstract: CSF-1 is the major regulator of tissue macrophage development and function. A GM-CSF-depen...
The proliferation, differentiation, and survival of cells of the macrophage lineage depends upon sig...
Colony stimulating factor-1 (CSF-1) regulates macrophage morphology and motility, as well as mononuc...
Macrophages are white blood cells involved in many aspects of host defence, immunity, pathology and ...
The receptor for human macrophage colony stimulating factor (CSF-1R) was introduced into hematopoiet...
CSF-1 regulates macrophage differentiation, survival, and function, and is an attractive therapeutic...
Macrophage colony-stimulating factor (CSF-1) binds to a receptor (CSF-1R) encoded by the c-fms proto...
peer reviewedThe proliferation, differentiation and survival of mononuclear phagocytes depend on sig...
The proliferation, differentiation, and survival of cells of the mononuclear phagocyte system (MPS; ...
Activation of the granulocyte-macrophage colony-stimulating factor (GM-CSF) family of receptors prom...
Macrophage activation is a key determinant of susceptibility and pathology in a variety of inflammat...
Already 20 years have passed since the cloning of the granulocyte- macrophage colony-stimulating fac...
The proliferation, differentiation and survival of mononuclear phagocytes depend on signals from the...
Homozygous mutation of the Csf1r locus (Csf1rko) in mice, rats and humans leads to multiple postnata...
There is recent interest in the role of monocyte/macrophage subpopulations in pathology. How the hem...
Abstract: CSF-1 is the major regulator of tissue macrophage development and function. A GM-CSF-depen...
The proliferation, differentiation, and survival of cells of the macrophage lineage depends upon sig...
Colony stimulating factor-1 (CSF-1) regulates macrophage morphology and motility, as well as mononuc...
Macrophages are white blood cells involved in many aspects of host defence, immunity, pathology and ...
The receptor for human macrophage colony stimulating factor (CSF-1R) was introduced into hematopoiet...
CSF-1 regulates macrophage differentiation, survival, and function, and is an attractive therapeutic...
Macrophage colony-stimulating factor (CSF-1) binds to a receptor (CSF-1R) encoded by the c-fms proto...
peer reviewedThe proliferation, differentiation and survival of mononuclear phagocytes depend on sig...
The proliferation, differentiation, and survival of cells of the mononuclear phagocyte system (MPS; ...
Activation of the granulocyte-macrophage colony-stimulating factor (GM-CSF) family of receptors prom...
Macrophage activation is a key determinant of susceptibility and pathology in a variety of inflammat...
Already 20 years have passed since the cloning of the granulocyte- macrophage colony-stimulating fac...
The proliferation, differentiation and survival of mononuclear phagocytes depend on signals from the...
Homozygous mutation of the Csf1r locus (Csf1rko) in mice, rats and humans leads to multiple postnata...
There is recent interest in the role of monocyte/macrophage subpopulations in pathology. How the hem...