Inaccuracy of Lipid Measurements with the Portable Cholestech LDX Analyzer in Patients with Hypercholesterolemia

measured by portable lipid analyzers have acceptable bias and precision in young and middle-aged adults, clinically relevant differences in HDL-cholesterol (HDL-C) and triglyceride values have been described. Furthermore, the accuracy of portable lipid analyzers in older hyperlipidemic individuals, who have a high incidence of coronary heart disease, has not been vali-dated. This study determined the biases and variability in portable lipid measurements in older patients with hypercholesterolemia and related them to National Cho-lesterol Education Program Adult Treatment Panel III guidelines. Methods: Participants were>70 years of age with fast-ing serum LDL-cholesterol (LDL-C) concentrations>1.40 g/L. Fasting fingerstick samples were analyzed on a Cholestech LDX desktop analyzer. Antecubital ve