Case Report: Changes in Creatine Kinase Isoenzymes after Myocardial Infarction in a Patient with Prostatic Carcinoma

The detection of serum proteins that can serve as tumor markers has been reported with increased frequency in patientswithvarious localizedormetastatic cancers. Many of these reportshave concerned patientswithprostatic carcinoma, who had normal or increased concentrations of creatine kinase (EC 2.7.3.2)inserum. In many instances the creatinekinaseBB isoenzyme was increasedinthese patients. I describe the case of a patient with carcinoma of the prostate(stage D), who had a myocardialinfarction threeto fourdays afteradmission.The serum activity of the MM, MB, and BB isoenzymes changed markedly after the infarction.These changes and the possible tissue source(s) of this isoenzyme are discussed in relationship to the clinical symptoms of the patient. Since the development of relatively rapid and sensitiv